Structure of PDB 1v1q Chain A Binding Site BS01

Receptor Information

>1v1q Chain A (length=110) Species: 83333 (Escherichia coli K-12)

PNSLMTNRLVLSGTVCRAPLRKVSPSGIPHCQFVLEHRSVQEEAGFHRQA
WCQMPVIVSGHENQAITHSITVGSRITVQGFISCHKAKNGLSKMVLHAEQ
IELIDSVDKL

Ligand information

• Ligand ID: CYS
• InChI: InChI=1S/C3H7NO2S/c4-2(1-7)3(5)6/h2,7H,1,4H2,(H,5,6)/t2-/m0/s1
• InChIKey: XUJNEKJLAYXESH-REOHCLBHSA-N
• SMILES:
  CACTVS 3.341: N[CH](CS)C(O)=O
  OpenEye OEToolkits 1.5.0: C([C@@H](C(=O)O)N)S
  CACTVS 3.341: N[C@@H](CS)C(O)=O
  ACDLabs 10.04: O=C(O)C(N)CS
  OpenEye OEToolkits 1.5.0: C(C(C(=O)O)N)S
• Formula: C3 H7 N O2 S
• Name: CYSTEINE
• ChEMBL: CHEMBL863
• DrugBank: DB00151
• ZINC: ZINC000000895042
• PDB chain: 1v1q Chain A Residue 201

Receptor-Ligand Complex Structure

Structure summary

• PDB: 1v1q Crystal Structure of Prib- a Primosomal DNA Replication Protein of Escherichia Coli
• Resolution: 2.1 Å
• Binding residue (original residue number in PDB): C12 R13 V30 Q49
• Binding residue (residue number reindexed from 1): C16 R17 V34 Q53
• Annotation score: 4

Gene Ontology

Molecular Function

• GO:0003677 DNA binding
• GO:0003697 single-stranded DNA binding
• GO:0005515 protein binding
• GO:0042802 identical protein binding

Biological Process

• GO:0006260 DNA replication
• GO:0006268 DNA unwinding involved in DNA replication
• GO:0006269 DNA replication, synthesis of primer
• GO:0006270 DNA replication initiation
• GO:0006276 plasmid maintenance
• GO:0009314 response to radiation
• GO:0031297 replication fork processing

Cellular Component

• GO:0030894 replisome
• GO:1990077 primosome complex
• GO:1990099 pre-primosome complex
• GO:1990158 DnaB-DnaC-DnaT-PriA-PriB complex

External links

• PDB: RCSB:1v1q, PDBe:1v1q, PDBj:1v1q
• PDBsum: 1v1q
• PubMed: 15383524
• UniProt: P07013|PRIB_ECOLI Primosomal replication protein N (Gene Name=priB)