Structure of PDB 1us2 Chain A Binding Site BS01

Receptor Information
>1us2 Chain A (length=507) Species: 155077 (Cellvibrio japonicus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
IEVDMANGWRGNASGSTSHSGITYSADGVTFAALGDGVGAVFDIARPTTL
EDAVIAMVVNVSAEFKASEANLQIFAQLKEDWSKGEWDCLAASSELTTDL
TLTCTIDEDDDKFNQTARDVQVGIQAKGTPAGTITIKSVTITLAYSANVD
HLRDLAPSDFPIGVAVSNTDSATYNLLTNSREQAVVKKHFNHLTAGNIMK
MSYMQPTEGNFNFTNADAFVDWATENNMTVHGHALVWHSDYQVPNFMKNW
AGSAEDFLAALDTHITTIVDHYEAKGNLVSWDVVNAAIDDNSPANFRTTD
SAFYVKSGNSSVYIERAFQTARAADPAVILYYNDYNIEQNNAKTTKMVDM
VKDFQARSIPIDGVGFQMHVCMNYPSIANISAAMKKVVDLGLLVKITELD
VAVNQPHCDAYPANKINPLTEAAQLAQKKRYCDVVKAYLDTVPVNQRGGI
SVWGTTDANTWLDGLYREQFEDEKISWPLLFDNNYNDKPALRGFADALIG
TQCTNTH
Ligand information
Ligand IDXYP
InChIInChI=1S/C5H10O5/c6-2-1-10-5(9)4(8)3(2)7/h2-9H,1H2/t2-,3+,4-,5-/m1/s1
InChIKeySRBFZHDQGSBBOR-KKQCNMDGSA-N
SMILES
SoftwareSMILES
OpenEye OEToolkits 1.5.0C1C(C(C(C(O1)O)O)O)O
CACTVS 3.341O[C@@H]1CO[C@@H](O)[C@H](O)[C@H]1O
OpenEye OEToolkits 1.5.0C1[C@H]([C@@H]([C@H]([C@@H](O1)O)O)O)O
CACTVS 3.341O[CH]1CO[CH](O)[CH](O)[CH]1O
ACDLabs 10.04OC1C(O)COC(O)C1O
FormulaC5 H10 O5
Namebeta-D-xylopyranose;
beta-D-xylose;
D-xylose;
xylose
ChEMBL
DrugBank
ZINCZINC000001529215
PDB chain1us2 Chain B Residue 1 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB1us2 Structural and Biochemical Analysis of Cellvibrio Japonicus Xylanase 10C: How Variation in Substrate-Binding Cleft Influences the Catalytic Profile of Family Gh-10 Xylanases
Resolution1.85 Å
Binding residue
(original residue number in PDB)		K299 H332 N384 Q466 E497 W552 W560
Binding residue
(residue number reindexed from 1)		K200 H233 N285 Q367 E398 W453 W461
Annotation score4
Enzymatic activity
Catalytic site (original residue number in PDB) A385 N432 H468 E497 D499
Catalytic site (residue number reindexed from 1) A286 N333 H369 E398 D400
Enzyme Commision number 3.2.1.8: endo-1,4-beta-xylanase.
Gene Ontology
Molecular Function
GO:0004553 hydrolase activity, hydrolyzing O-glycosyl compounds
Biological Process
GO:0005975 carbohydrate metabolic process

View graph for
Molecular Function
View graph for
Biological Process
External links
PDB RCSB:1us2, PDBe:1us2, PDBj:1us2
PDBsum1us2
PubMed14670951
UniProtQ59675|XY10C_CELJA Endo-beta-1,4-xylanase Xyn10C (Gene Name=xyn10C)

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