Structure of PDB 1um2 Chain A Binding Site BS01

Receptor Information
>1um2 Chain A (length=417) Species: 4932 (Saccharomyces cerevisiae) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SFAKGTNVLMADGSIECIENIEVGNKVMGKDGRPREVIKLPRGRETMYSV
VQKSPELLKFTCNATNELVVRTPRSVRRLSRTIKGVEYFEVITFEMGQKK
APDGRIVELVKEVSKSYPISEGPERANELVESYRKASNKAYFEWTIEARD
LSLLGSHVRKATYQTYAPILYENDHFFDYMQKSKFHLTIEGPKVLAYLLG
LWIGDGLSDRATFSVDSRDTSLMERVTEYAEKLNLCAEYKDRKEPQVAKT
VNLYSKENPLWDAIVGLGFLKDGVKNIPSFLSTDNIGTRETFLAGLIDSD
GYVTDEHGIKATIKTIHTSVRDGLVSLARSLGLVVSVNAEPISYAIYMSG
GDVLLNVLSKCAGSKKFRPAPAAAFARECRGFYFELQELKEDDYYGITLS
DDSDHQFLLANQVVVHN
Ligand information
Receptor-Ligand Complex Structure
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PDB1um2 Protein splicing of yeast VMA1-derived endonuclease via thiazolidine intermediates.
Resolution2.9 Å
Binding residue
(original residue number in PDB)		S284 F285 P324 N359 E363 G716 T718 N737
Binding residue
(residue number reindexed from 1)		S1 F2 P41 N63 E67 G396 T398 N417
Enzymatic activity
Catalytic site (original residue number in PDB) S284 N359 T361 N362 K584 K686 G716 I717 N737
Catalytic site (residue number reindexed from 1) S1 N63 T65 N66 K275 K366 G396 I397 N417
Enzyme Commision number 3.1.-.-
7.1.2.2: H(+)-transporting two-sector ATPase.
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0004519 endonuclease activity
Biological Process
GO:0016539 intein-mediated protein splicing
GO:0030908 protein splicing

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Molecular Function
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Biological Process
External links
PDB RCSB:1um2, PDBe:1um2, PDBj:1um2
PDBsum1um2
PubMed14646148
UniProtP17255|VATA_YEAST V-type proton ATPase catalytic subunit A (Gene Name=VMA1)

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