Structure of PDB 1uas Chain A Binding Site BS01

Receptor Information
>1uas Chain A (length=362) Species: 4530 (Oryza sativa) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
FENGLGRTPQMGWNSWNHFYCGINEQIIRETADALVNTGLAKLGYQYVNI
DDCWAEYSRDSQGNFVPNRQTFPSGIKALADYVHAKGLKLGIYSDAGSQT
CSNKMPGSLDHEEQDVKTFASWGVDYLKYDNCNDAGRSVMERYTRMSNAM
KTYGKNIFFSLCEWGKENPATWAGRMGNSWRTTGDIADNWGSMTSRADEN
DQWAAYAGPGGWNDPDMLEVGNGGMSEAEYRSHFSIWALAKAPLLIGCDV
RSMSQQTKNILSNSEVIAVNQDSLGVQGKKVQSDNGLEVWAGPLSNNRKA
VVLWNRQSYQATITAHWSNIGLAGSVAVTARDLWAHSSFAAQGQISASVA
PHDCKMYVLTPN
Ligand information
Ligand IDGLA
InChIInChI=1S/C6H12O6/c7-1-2-3(8)4(9)5(10)6(11)12-2/h2-11H,1H2/t2-,3+,4+,5-,6+/m1/s1
InChIKeyWQZGKKKJIJFFOK-PHYPRBDBSA-N
SMILES
SoftwareSMILES
CACTVS 3.341OC[C@H]1O[C@H](O)[C@H](O)[C@@H](O)[C@H]1O
OpenEye OEToolkits 1.5.0C(C1C(C(C(C(O1)O)O)O)O)O
OpenEye OEToolkits 1.5.0C([C@@H]1[C@@H]([C@@H]([C@H]([C@H](O1)O)O)O)O)O
CACTVS 3.341OC[CH]1O[CH](O)[CH](O)[CH](O)[CH]1O
ACDLabs 10.04OC1C(O)C(OC(O)C1O)CO
FormulaC6 H12 O6
Namealpha-D-galactopyranose;
alpha-D-galactose;
D-galactose;
galactose;
ALPHA D-GALACTOSE
ChEMBLCHEMBL1233058
DrugBank
ZINCZINC000000901155
PDB chain1uas Chain A Residue 1501 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB1uas Crystal structure of rice alpha-galactosidase complexed with D-galactose
Resolution1.5 Å
Binding residue
(original residue number in PDB)		W16 D51 D52 C101 K128 D130 C162 W164 R181 D185
Binding residue
(residue number reindexed from 1)		W16 D51 D52 C101 K128 D130 C162 W164 R181 D185
Annotation score5
Enzymatic activity
Catalytic site (original residue number in PDB) D130 D185
Catalytic site (residue number reindexed from 1) D130 D185
Enzyme Commision number 3.2.1.22: alpha-galactosidase.
Gene Ontology
Molecular Function
GO:0004553 hydrolase activity, hydrolyzing O-glycosyl compounds
GO:0004557 alpha-galactosidase activity
GO:0016798 hydrolase activity, acting on glycosyl bonds
GO:0052692 raffinose alpha-galactosidase activity
Biological Process
GO:0000272 polysaccharide catabolic process
GO:0005975 carbohydrate metabolic process
GO:0009620 response to fungus
GO:0009911 positive regulation of flower development
GO:0009965 leaf morphogenesis
GO:0051682 galactomannan catabolic process
Cellular Component
GO:0009505 plant-type cell wall
GO:0048046 apoplast

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:1uas, PDBe:1uas, PDBj:1uas
PDBsum1uas
PubMed12657636
UniProtQ9FXT4|AGAL_ORYSJ Alpha-galactosidase (Gene Name=Os10g0493600)

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