Structure of PDB 1u3r Chain A Binding Site BS01

Receptor Information
>1u3r Chain A (length=231) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
LSPEQLVLTLLEAEPPHVLISRPSAPFTEASMMMSLTKLADKELVHMISW
AKKIPGFVELSLFDQVRLLESCWMEVLMMGLMWRSIDHPGKLIFAPDLVL
DRDEGKCVEGILEIFDMLLATTSRFRELKLQHKEYLCVKAMILLNSSMQD
ADSSRKLAHLLNAVTDALVWVIAKSGISSQQQSMRLANLLMLLSHVRHAS
NKGMEHLLNMKCKNVVPVYDLLLEMLNAHVL
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB1u3r Design and synthesis of aryl diphenolic azoles as potent and selective estrogen receptor-beta ligands.
Resolution2.21 Å
Binding residue
(original residue number in PDB)		I310 K314 E493
Binding residue
(residue number reindexed from 1)		I48 K52 E224
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0004879 nuclear receptor activity
Biological Process
GO:0006355 regulation of DNA-templated transcription

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Molecular Function
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Biological Process
External links
PDB RCSB:1u3r, PDBe:1u3r, PDBj:1u3r
PDBsum1u3r
PubMed15456246
UniProtQ92731|ESR2_HUMAN Estrogen receptor beta (Gene Name=ESR2)

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