Structure of PDB 1u1n Chain A Binding Site BS01
Receptor Information
>1u1n Chain A (length=183) Species:
9606
(Homo sapiens) [
Search protein sequence
] [
Download receptor structure
] [
Download structure with residue number starting from 1
] [
View receptor structure
]
KEPEQLRKLFIGGLSFETTDESLRSHFEQWGTLTDCVVMRDPNTKRSRGF
GFVTYATVEEVDAAMNARPHKVDGRVVEPKRAVSREDSQRPGAHLTVKKI
FVGGIKEDTEEHHLRDYFEQYGKIEVIEIMTDRGSGKKRGFAFVTFDDHD
SVDKIVIQKYHTVNGHNCEVRKALSKQEMASAS
Ligand information
>1u1n Chain B (length=11) [
Search DNA sequence
] [
Download ligand structure
] [
Download structure with residue number starting from 1
] [
View ligand structure
]
tagggttaagg
Receptor-Ligand Complex Structure
Global view
Local view
Structure summary
[
Spin on
] [
Spin off
] [
Reset
]
[
High quality
] [
Low quality
]
[
White background
] [
Black background
]
[
Spin on
] [
Spin off
] [
Reset
]
[
High quality
] [
Low quality
]
[
White background
] [
Black background
]
PDB
1u1n
Human UP1 as a Model for Understanding Purine Recognition in the Family of Proteins Containing the RNA Recognition Motif (RRM).
Resolution
2.1 Å
Binding residue
(original residue number in PDB)
Q12 K15 F17 G19 G20 D42 V44 M46 R55 F57 F59 E85 A89 V90 R92 S95 H101
Binding residue
(residue number reindexed from 1)
Q5 K8 F10 G12 G13 D35 V37 M39 R48 F50 F52 E78 A82 V83 R85 S88 H94
Binding affinity
PDBbind-CN
: Kd=316nM
Enzymatic activity
Enzyme Commision number
?
Gene Ontology
Molecular Function
GO:0003676
nucleic acid binding
GO:0003723
RNA binding
View graph for
Molecular Function
External links
PDB
RCSB:1u1n
,
PDBe:1u1n
,
PDBj:1u1n
PDBsum
1u1n
PubMed
15342234
UniProt
P09651
|ROA1_HUMAN Heterogeneous nuclear ribonucleoprotein A1 (Gene Name=HNRNPA1)
[
Back to BioLiP
]