Structure of PDB 1u12 Chain A Binding Site BS01

Receptor Information
>1u12 Chain A (length=131) Species: 266835 (Mesorhizobium japonicum MAFF 303099) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
RRGDFVRNWQLVAAVPLFQKLGPAVLVEIVRALRARTVPAGAVICRIGEP
GDRMFFVVEGSVSVATPNPVELGPGAFFGEMALISGEPRSATVSAATTVS
LLSLHSADFQMLCSSSPEIAEIFRKTALEAR
Ligand information
Ligand IDK
InChIInChI=1S/K/q+1
InChIKeyNPYPAHLBTDXSSS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
CACTVS 3.341
OpenEye OEToolkits 1.5.0		[K+]
FormulaK
NamePOTASSIUM ION
ChEMBLCHEMBL1233793
DrugBankDB01345
ZINC
PDB chain1u12 Chain A Residue 814 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB1u12 Structural Basis of Ligand Activation in a Cyclic Nucleotide Regulated Potassium Channel
Resolution2.7 Å
Binding residue
(original residue number in PDB)		S279 E289 L290 G291
Binding residue
(residue number reindexed from 1)		S61 E71 L72 G73
Annotation score3
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0005221 intracellularly cyclic nucleotide-activated monoatomic cation channel activity

View graph for
Molecular Function
External links
PDB RCSB:1u12, PDBe:1u12, PDBj:1u12
PDBsum1u12
PubMed15550244
UniProtQ98GN8|CNGK1_RHILO Cyclic nucleotide-gated potassium channel mll3241 (Gene Name=mll3241)

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