Structure of PDB 1tzz Chain A Binding Site BS01

Receptor Information
>1tzz Chain A (length=374) Species: 375 (Bradyrhizobium japonicum) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
VRIVDVREITKPISSTKMTTSLVAVVTDVVREGKRVVGYGFNSNGRYGQG
GLIRERFASRILEADPKKLLNEAGDNLDPDKVWAAMMINEKPGGHGERSV
AVGTIDMAVWDAVAKIAGKPLFRLLAERHGVKANPRVFVYAAGGYYGLSM
LRGEMRGYLDRGYNVVKMKIGGAPIEEDRMRIEAVLEEIGKDAQLAVDAN
GRFNLETGIAYAKMLRDYPLFWYEEVGDPLDYALQAALAEFYPGPMATGE
NLFSHQDARNLLRYGGMRPDRDWLQFDCALSYGLCEYQRTLEVLKTHGWS
PSRCIPHGGHQMSLNIAAGLGLGGNESYPDLFQPYGGFPDGVRVENGHIT
MPDLPGIGFEGKSDLYKEMKALAE
Ligand information
Ligand IDMG
InChIInChI=1S/Mg/q+2
InChIKeyJLVVSXFLKOJNIY-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Mg+2]
CACTVS 3.341[Mg++]
FormulaMg
NameMAGNESIUM ION
ChEMBL
DrugBankDB01378
ZINC
PDB chain1tzz Chain A Residue 3501 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB1tzz Crystal structure of the protein L1841, unknown member of enolase superfamily from Bradyrhizobium japonicum
Resolution1.86 Å
Binding residue
(original residue number in PDB)		D1216 E1242 E1268
Binding residue
(residue number reindexed from 1)		D198 E224 E250
Annotation score1
Enzymatic activity
Catalytic site (original residue number in PDB) N1058 K1185 K1187 D1216 N1218 E1242 G1267 E1268 D1295 H1325 E1344 D1348
Catalytic site (residue number reindexed from 1) N44 K167 K169 D198 N200 E224 G249 E250 D277 H307 E326 D330
Enzyme Commision number 4.2.1.81: D(-)-tartrate dehydratase.
Gene Ontology
Molecular Function
GO:0000287 magnesium ion binding
GO:0003824 catalytic activity
GO:0016829 lyase activity
GO:0046872 metal ion binding
GO:0047808 D(-)-tartrate dehydratase activity
Biological Process
GO:0051260 protein homooligomerization

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Molecular Function
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Biological Process
External links
PDB RCSB:1tzz, PDBe:1tzz, PDBj:1tzz
PDBsum1tzz
PubMed
UniProtQ89FH0|TARD_BRADU D(-)-tartrate dehydratase (Gene Name=tarD)

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