Structure of PDB 1tzf Chain A Binding Site BS01

Receptor Information
>1tzf Chain A (length=251) Species: 220341 (Salmonella enterica subsp. enterica serovar Typhi str. CT18) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MASKAVILAGGLGVKPKPMVEIGGKPILWHIMKMYSVHGIKDFIICCGYK
GYVIKEYFANYFLHMSDVTFHMAENRMEVHHKRVEPWNVTLVDTGDSSMT
GGRLKRVAEYVKDDEAFLFTYGDGVADLDIKATIDFHKAHGKKATLTATF
PPGRFGALDIQAGQVRSFQEKPKGDGAMINGGFFVLNPSVIDLIDNDATT
WEQEPLMTLAQQGELMAFEHPGFWQPMDTLRDKVYLEGLWEKGKAPWKTW
E
Ligand information
Ligand IDMG
InChIInChI=1S/Mg/q+2
InChIKeyJLVVSXFLKOJNIY-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Mg+2]
CACTVS 3.341[Mg++]
FormulaMg
NameMAGNESIUM ION
ChEMBL
DrugBankDB01378
ZINC
PDB chain1tzf Chain A Residue 403 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB1tzf Molecular structure of alpha-D-glucose-1-phosphate cytidylyltransferase from Salmonella typhi
Resolution2.1 Å
Binding residue
(original residue number in PDB)		D131 D236
Binding residue
(residue number reindexed from 1)		D123 D228
Annotation score1
Enzymatic activity
Enzyme Commision number 2.7.7.33: glucose-1-phosphate cytidylyltransferase.
Gene Ontology
Molecular Function
GO:0000166 nucleotide binding
GO:0016779 nucleotidyltransferase activity
GO:0046872 metal ion binding
GO:0047343 glucose-1-phosphate cytidylyltransferase activity
Biological Process
GO:0009058 biosynthetic process
GO:0009103 lipopolysaccharide biosynthetic process
GO:0009243 O antigen biosynthetic process

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Molecular Function
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Biological Process
External links
PDB RCSB:1tzf, PDBe:1tzf, PDBj:1tzf
PDBsum1tzf
PubMed15292268
UniProtQ8Z5I4|RFBF_SALTI Glucose-1-phosphate cytidylyltransferase (Gene Name=rfbF)

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