Structure of PDB 1tvh Chain A Binding Site BS01
Receptor Information
>1tvh Chain A (length=275) Species:
9606
(Homo sapiens) [
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GSHSMRYFFTSVSRPGRGEPRFIAVGYVDDTQFVRFDSDAASQRMEPRAP
WIEQEGPEYWDGETRKVKAHSQTHRVDLGTLRGYYNQSEAGSHTVQRMYG
CDVGSDWRFLRGYHQYAYDGKDYIALKEDLRSWTAADMAAQTTKHKWEAA
HVAEQLRAYLEGTCVEWLRRYLENGKETLQRTDAPKTHMTHHAVSDHEAT
LRCWALSFYPAEITLTWQRDGEDQTQDTELVETRPAGDGTFQKWAAVVVP
SGQEQRYTCHVQHEGLPKPLTLRWE
Ligand information
>1tvh Chain C (length=9) Species:
9606
(Homo sapiens) [
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IMDQVPFSV
Receptor-Ligand Complex Structure
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PDB
1tvh
Increased Immunogenicity of an Anchor-Modified Tumor-Associated Antigen Is Due to the Enhanced Stability of the Peptide/MHC Complex: Implications for Vaccine Design
Resolution
1.802 Å
Binding residue
(original residue number in PDB)
Y7 E63 K66 V67 H70 T73 D77 Y84 R97 Y99 Y116 T143 W147 A150 Y159 T163 W167 Y171
Binding residue
(residue number reindexed from 1)
Y7 E63 K66 V67 H70 T73 D77 Y84 R97 Y99 Y116 T143 W147 A150 Y159 T163 W167 Y171
Enzymatic activity
Enzyme Commision number
?
External links
PDB
RCSB:1tvh
,
PDBe:1tvh
,
PDBj:1tvh
PDBsum
1tvh
PubMed
15814707
UniProt
P04439
|HLAA_HUMAN HLA class I histocompatibility antigen, A alpha chain (Gene Name=HLA-A)
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