Structure of PDB 1tro Chain A Binding Site BS01

Receptor Information
>1tro Chain A (length=104) Species: 316407 (Escherichia coli str. K-12 substr. W3110) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SPYSAAMAEERHQEWLRFVDLLKNAYQNDLHLPLLNLMLTPDEREALGTR
VRIVEELLRGEMSQRELKNELGAGIATITRGSNSLKAAPVELRQWLEEVL
LKSD
Ligand information
Receptor-Ligand Complex Structure
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PDB1tro Crystal structure of trp repressor/operator complex at atomic resolution.
Resolution1.9 Å
Binding residue
(original residue number in PDB)		T44 D46 S67 Q68 R69 T83 S86 N87 K90
Binding residue
(residue number reindexed from 1)		T40 D42 S63 Q64 R65 T79 S82 N83 K86
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0003700 DNA-binding transcription factor activity
GO:0043565 sequence-specific DNA binding
Biological Process
GO:0006355 regulation of DNA-templated transcription
GO:0045892 negative regulation of DNA-templated transcription
Cellular Component
GO:0005737 cytoplasm

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Cellular Component
External links
PDB RCSB:1tro, PDBe:1tro, PDBj:1tro
PDBsum1tro
PubMed3419502
UniProtP0A881|TRPR_ECOLI Trp operon repressor (Gene Name=trpR)

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