Structure of PDB 1top Chain A Binding Site BS01

Receptor Information
>1top Chain A (length=162) Species: 9031 (Gallus gallus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
ASMTDQQAEARAFLSEEMIAEFKAAFDMFDADGGGDISTKELGTVMRMLG
QNPTKEELDAIIEEVDEDGSGTIDFEEFLVMMVRQMKEDAKGKSEEELAN
CFRIFDKNADGFIDIEELGEILRATGEHVTEEDIEDLMKDSDKNNDGRID
FDEFLKMMEGVQ
Ligand information
Ligand IDCA
InChIInChI=1S/Ca/q+2
InChIKeyBHPQYMZQTOCNFJ-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Ca++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Ca+2]
FormulaCa
NameCALCIUM ION
ChEMBL
DrugBankDB14577
ZINC
PDB chain1top Chain A Residue 163 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB1top Structure of chicken skeletal muscle troponin C at 1.78 A resolution.
Resolution1.78 Å
Binding residue
(original residue number in PDB)		D106 N108 D110 F112 E117
Binding residue
(residue number reindexed from 1)		D106 N108 D110 F112 E117
Annotation score4
Enzymatic activity
Catalytic site (original residue number in PDB) V45
Catalytic site (residue number reindexed from 1) V45
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0005509 calcium ion binding
GO:0046872 metal ion binding
Biological Process
GO:0003009 skeletal muscle contraction
Cellular Component
GO:0005861 troponin complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:1top, PDBe:1top, PDBj:1top
PDBsum1top
PubMed15299475
UniProtP02588|TNNC2_CHICK Troponin C, skeletal muscle (Gene Name=TNNC2)

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