Structure of PDB 1tl4 Chain A Binding Site BS01

Receptor Information
>1tl4 Chain A (length=68) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MPKHEFSVDMTCGGCAEAVSRVLNKLGGVKYDIDLPNKKVCIESEHSMDT
LLATLKKTGKTVSYLGLE
Ligand information
Ligand IDCU1
InChIInChI=1S/Cu/q+1
InChIKeyVMQMZMRVKUZKQL-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
CACTVS 3.341
OpenEye OEToolkits 1.5.0		[Cu+]
FormulaCu
NameCOPPER (I) ION
ChEMBL
DrugBank
ZINC
PDB chain1tl4 Chain A Residue 69 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB1tl4 Solution Structure of the Apo and Copper(I)-Loaded Human Metallochaperone HAH1.
ResolutionN/A
Binding residue
(original residue number in PDB)		C12 C15
Binding residue
(residue number reindexed from 1)		C12 C15
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0005507 copper ion binding
GO:0005515 protein binding
GO:0016530 metallochaperone activity
GO:0016531 copper chaperone activity
GO:0032767 copper-dependent protein binding
GO:0046872 metal ion binding
GO:1903136 cuprous ion binding
Biological Process
GO:0006825 copper ion transport
GO:0006878 intracellular copper ion homeostasis
GO:0006979 response to oxidative stress
Cellular Component
GO:0005829 cytosol

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:1tl4, PDBe:1tl4, PDBj:1tl4
PDBsum1tl4
PubMed15476398
UniProtO00244|ATOX1_HUMAN Copper transport protein ATOX1 (Gene Name=ATOX1)

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