Structure of PDB 1tkp Chain A Binding Site BS01

Receptor Information
>1tkp Chain A (length=180) Species: 2242 (Halobacterium salinarum) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
STQKNARATAGEVEGSDALRMDADRAEQCVDALNADLANVYVLYHQLKKH
HWNVEGAEFRDLHLFLGEAAETAEEVADELAERVQALGGVPHASPETLQA
EASVDVEDEDVYDIRTSLANDMAIYGDIIEATREHTELAENLGDHATAHM
LREGLIELEDDAHHIEHYLEDDTLVTQGAL
Ligand information
Ligand IDFE
InChIInChI=1S/Fe/q+3
InChIKeyVTLYFUHAOXGGBS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
CACTVS 3.341
OpenEye OEToolkits 1.5.0		[Fe+3]
FormulaFe
NameFE (III) ION
ChEMBL
DrugBankDB13949
ZINC
PDB chain1tkp Chain A Residue 304 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB1tkp Iron-oxo clusters biomineralizing on protein surfaces: structural analysis of Halobacterium salinarum DpsA in its low- and high-iron states.
Resolution2.2 Å
Binding residue
(original residue number in PDB)		D79 E83
Binding residue
(residue number reindexed from 1)		D78 E82
Annotation score5
Enzymatic activity
Enzyme Commision number 1.16.-.-
Gene Ontology
Molecular Function
GO:0008199 ferric iron binding
GO:0016491 oxidoreductase activity
GO:0046872 metal ion binding
Biological Process
GO:0006879 intracellular iron ion homeostasis
Cellular Component
GO:0005737 cytoplasm

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:1tkp, PDBe:1tkp, PDBj:1tkp
PDBsum1tkp
PubMed15365182
UniProtQ9HMP7|DPS_HALSA DNA protection during starvation protein (Gene Name=dps)

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