Structure of PDB 1tfi Chain A Binding Site BS01

Receptor Information
>1tfi Chain A (length=50) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
KTGGTQTDLFTCGKCKKKNCTYTQVQTRSADEPMTTFVVCNECGNRWKFC
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain1tfi Chain A Residue 51 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB1tfi Novel zinc finger motif in the basal transcriptional machinery: three-dimensional NMR studies of the nucleic acid binding domain of transcriptional elongation factor TFIIS.
ResolutionN/A
Binding residue
(original residue number in PDB)		C12 C15 C40 C43
Binding residue
(residue number reindexed from 1)		C12 C15 C40 C43
Annotation score1
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003676 nucleic acid binding
GO:0003899 DNA-directed 5'-3' RNA polymerase activity
GO:0008270 zinc ion binding
Biological Process
GO:0006351 DNA-templated transcription

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Molecular Function
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Biological Process
External links
PDB RCSB:1tfi, PDBe:1tfi, PDBj:1tfi
PDBsum1tfi
PubMed8399164
UniProtP23193|TCEA1_HUMAN Transcription elongation factor A protein 1 (Gene Name=TCEA1)

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