Structure of PDB 1tbo Chain A Binding Site BS01

Receptor Information
>1tbo Chain A (length=66) Species: 10117 (Rattus rattus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
QTDDPRNKHKFRLHSYSSPTFCDHCGSLLYGLVHQGMKCSCCEMNVHRRC
VRSVPSLCGVDHTERR
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0
[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain1tbo Chain A Residue 1 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB1tbo NMR structure of a protein kinase C-gamma phorbol-binding domain and study of protein-lipid micelle interactions.
ResolutionN/A
Binding residue
(original residue number in PDB)
H102 C132 C135 C151
Binding residue
(residue number reindexed from 1)
H9 C39 C42 C58
Annotation score1
Enzymatic activity
Enzyme Commision number 2.7.11.13: protein kinase C.
External links
PDB RCSB:1tbo, PDBe:1tbo, PDBj:1tbo
PDBsum1tbo
PubMed9271501
UniProtP63319|KPCG_RAT Protein kinase C gamma type (Gene Name=Prkcg)

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