Structure of PDB 1t6k Chain A Binding Site BS01

Receptor Information
>1t6k Chain A (length=278) Species: 294 (Pseudomonas fluorescens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MHNYVIIDAFASVPLEGNPVAVFFDADDLPPAQMQRIAREMNLSESTFVL
KPRNGGDALIRIFTPVNELPFAGHPLLGTAIALGAHTDNHRLYLETQMGT
IAFELERQNGSVIAASMDQPIPTWTALGRDAELLKALGISDSTFPIEIYH
NGPRHVFVGLPSIDALSALHPDHRALSNFHDMAINCFAGAGRRWRSRMFS
PAYGVVEDAATGSAAGPLAIHLARHGQIEFGQPVEILQGVEIGRPSLMFA
KAEGRAEQLTRVEVSGNGVTFGRGTIVL
Ligand information
Ligand IDSO4
InChIInChI=1S/H2O4S/c1-5(2,3)4/h(H2,1,2,3,4)/p-2
InChIKeyQAOWNCQODCNURD-UHFFFAOYSA-L
SMILES
SoftwareSMILES
OpenEye OEToolkits 1.5.0[O-]S(=O)(=O)[O-]
CACTVS 3.341[O-][S]([O-])(=O)=O
ACDLabs 10.04[O-]S([O-])(=O)=O
FormulaO4 S
NameSULFATE ION
ChEMBL
DrugBankDB14546
ZINC
PDB chain1t6k Chain A Residue 301 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB1t6k Structure and function of the phenazine biosynthesis protein PhzF from Pseudomonas fluorescens 2-79
Resolution1.8 Å
Binding residue
(original residue number in PDB)		A72 G73 H74 T211 G212 S213
Binding residue
(residue number reindexed from 1)		A72 G73 H74 T211 G212 S213
Annotation score1
Enzymatic activity
Enzyme Commision number 5.3.3.17: trans-2,3-dihydro-3-hydroxyanthranilate isomerase.
Gene Ontology
Molecular Function
GO:0003824 catalytic activity
GO:0016853 isomerase activity
GO:0102943 trans-2,3-dihydro-3-hydroxy-anthranilate isomerase activity
Biological Process
GO:0002047 phenazine biosynthetic process
GO:0009058 biosynthetic process
GO:0017000 antibiotic biosynthetic process
Cellular Component
GO:0005737 cytoplasm

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:1t6k, PDBe:1t6k, PDBj:1t6k
PDBsum1t6k
PubMed15449932
UniProtQ51792|PHZF_PSEFL Trans-2,3-dihydro-3-hydroxyanthranilate isomerase (Gene Name=phzF)

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