Structure of PDB 1t4w Chain A Binding Site BS01

Receptor Information
>1t4w Chain A (length=196) Species: 6239 (Caenorhabditis elegans) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
EKWMEIDVLKQKVAKSSDMAFAISSEHEKYLWTKMGCLVPIQVKWKLDKR
HFNSNLSLRIRFVKYDKKENVEYAIRNPRSDVMKCRSHTEREQHFPFDSF
FYIRNSEHEFSYSAEKGSTFTLIMYPGAVQANFDIIFMCQEKCLDLDDRR
KTMCLAVFLDDENGNEILHAYIKQVRIVAYPRRDWKNFCEREDAKQ
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain1t4w Chain A Residue 201 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB1t4w Structural Differences in the DNA Binding Domains of Human p53 and Its C. elegans Ortholog Cep-1.
Resolution2.1 Å
Binding residue
(original residue number in PDB)		C307 H310 C361 C365
Binding residue
(residue number reindexed from 1)		C85 H88 C139 C143
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0003700 DNA-binding transcription factor activity
Biological Process
GO:0006355 regulation of DNA-templated transcription
Cellular Component
GO:0005634 nucleus

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:1t4w, PDBe:1t4w, PDBj:1t4w
PDBsum1t4w
PubMed15242600
UniProtQ20646|CEP1_CAEEL Transcription factor cep-1 (Gene Name=cep-1)

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