Structure of PDB 1t4g Chain A Binding Site BS01

Receptor Information

>1t4g Chain A (length=299) Species: 2188 (Methanococcus voltae)

LTDLPGVGPSTAEKLVEAGYIDFMKIATATVGELTDIEGISEKAAAKMIM
GARDLCDLGFKSGIDLLKQRSTVWKLSTSSSELDSVLGGGLESQSVTEFA
GVFGSGKTQIMHQSCVNLQNPEFLFYDEEAVSKGEVAQPKAVYIDTEGTF
RPERIMQMAEHAGIDGQTVLDNTFVARAYNSDMQMLFAEKIEDLIQEGNN
IKLVVIDSLTSTFRNEYTGRGKLAERQQKLGRHMATLNKLADLFNCVVLV
TNQVSGHAATFRFFVRKGKGDKRVAKLYDSPHLPDAEAIFRITEKGIQD

Ligand information

• Ligand ID: MG
• InChI: InChI=1S/Mg/q+2
• InChIKey: JLVVSXFLKOJNIY-UHFFFAOYSA-N
• SMILES:
  ACDLabs 10.04
  OpenEye OEToolkits 1.5.0: [Mg+2]
  CACTVS 3.341: [Mg++]
• Formula: Mg
• Name: MAGNESIUM ION
• DrugBank: DB01378
• PDB chain: 1t4g Chain A Residue 502

Receptor-Ligand Complex Structure

Structure summary

• PDB: 1t4g Crystal Structure of Archaeal Recombinase RadA; A Snapshot of Its Extended Conformation.
• Resolution: 2.0 Å
• Binding residue (original residue number in PDB): Q98 D246
• Binding residue (residue number reindexed from 1): Q94 D242
• Annotation score: 1

Gene Ontology

Molecular Function

• GO:0000166 nucleotide binding
• GO:0003677 DNA binding
• GO:0003684 damaged DNA binding
• GO:0005524 ATP binding
• GO:0008094 ATP-dependent activity, acting on DNA
• GO:0016887 ATP hydrolysis activity
• GO:0042802 identical protein binding
• GO:0140664 ATP-dependent DNA damage sensor activity

Biological Process

• GO:0006259 DNA metabolic process
• GO:0006281 DNA repair
• GO:0006310 DNA recombination
• GO:0006974 DNA damage response

External links

• PDB: RCSB:1t4g, PDBe:1t4g, PDBj:1t4g
• PDBsum: 1t4g
• PubMed: 15304222
• UniProt: O73948|RADA_METVO DNA repair and recombination protein RadA (Gene Name=radA)