Structure of PDB 1t3l Chain A Binding Site BS01

Receptor Information
>1t3l Chain A (length=306) Species: 9986 (Oryctolagus cuniculus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
LEEDREAVRREAERQAQAQLEKAKTKPVAFAVRTNVSYSAAHEDDVPVPG
MAISFEAKDFLHVKEKFNNDWWIGRLVKEGCEIGFIPSRVKLENMRLQHE
QRAKEFKLTPPYDVVPSMRPVVLVGPSLKGYEVTDMMQKALFDFLKHRFE
GRISITRVTADISLAKRSVLNNPSKHAIIERSNTRSSLAEVQSEIERIFE
LARTLQLVVLDADTINHPAQLSKTSLAPIVVYVKISSPKVLQRLIKSRGK
SQAKHLNVQMVAADKLAQCPPELFDVILDENQLEDACEHLADYLEAYWKA
THPPSS
Ligand information
>1t3l Chain B (length=17) Species: 9986 (Oryctolagus cuniculus) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
QLEEDLRGYMSWITQGE
Receptor-Ligand Complex Structure
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PDB1t3l Structural Analysis of Voltage-Dependent Calcium Channel Beta Subunit Functional Core and Its Complex with the Alpha1 Interaction Domain
Resolution2.2 Å
Binding residue
(original residue number in PDB)		M245 M246 V349 R352 L353 S356 E389 N390 L392
Binding residue
(residue number reindexed from 1)		M136 M137 V240 R243 L244 S247 E280 N281 L283
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0005245 voltage-gated calcium channel activity
Biological Process
GO:0070588 calcium ion transmembrane transport
Cellular Component
GO:0005891 voltage-gated calcium channel complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:1t3l, PDBe:1t3l, PDBj:1t3l
PDBsum1t3l
PubMed15134636
UniProtP54288|CACB2_RABIT Voltage-dependent L-type calcium channel subunit beta-2 (Gene Name=CACNB2)

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