Structure of PDB 1t22 Chain A Binding Site BS01

Receptor Information
>1t22 Chain A (length=275) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GSHSMRYFFTSVSRPGRGEPRFIAVGYVDDTQFVRFDSDAASQRMEPRAP
WIEQEGPEYWDGETRKVKAHSQTHRVDLGTLRGYYNQSEAGSHTVQRMYG
CDVGSDWRFLRGYHQYAYDGKDYIALKEDLRSWTAADMAAQTTKHKWEAA
HVAEQLRAYLEGTCVEWLRRYLENGKETLQRTDAPKTHMTHHAVSDHEAT
LRCWALSFYPAEITLTWQRDGEDQTQDTELVETRPAGDGTFQKWAAVVVP
SGQEQRYTCHVQHEGLPKPLTLRWE
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB1t22 Structural Basis for Degenerate Recognition of Natural HIV Peptide Variants by Cytotoxic Lymphocytes.
Resolution2.2 Å
Binding residue
(original residue number in PDB)
M5 Y7 E63 K66 V67 H70 T73 V76 D77 L81 Y84 Y99 Y116 T143 W147 L156 Y159 W167 Y171
Binding residue
(residue number reindexed from 1)
M5 Y7 E63 K66 V67 H70 T73 V76 D77 L81 Y84 Y99 Y116 T143 W147 L156 Y159 W167 Y171
Enzymatic activity
Enzyme Commision number ?
External links
PDB RCSB:1t22, PDBe:1t22, PDBj:1t22
PDBsum1t22
PubMed16702212
UniProtP04439|HLAA_HUMAN HLA class I histocompatibility antigen, A alpha chain (Gene Name=HLA-A)

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