Structure of PDB 1sz6 Chain A Binding Site BS01

Receptor Information
>1sz6 Chain A (length=249) Species: 3972 (Viscum album) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
YERLSLRTVQQTTGAEYFSFITLLRDFVSSGSFSNNIPLLRQSTIPVSEG
SRFVLVELTNAGGDSITAAIDVTNLYVVAYQAGQQSYFLKDAPAGAETQD
FAGTTRSSLPFNGSYPDLERYAGHRDQIPLGIDQLIASVTALRFPGGSTR
TQARSILILIQMISEAARFNPILWRARQYINSGASFLPDVYMLELETSWG
QQSTQVQHSTDGVFNNPIALALPPGNVVTLTNIRDVIASLAIMLFVCGE
Ligand information
Ligand IDAZI
InChIInChI=1S/N3/c1-3-2/q-1
InChIKeyIVRMZWNICZWHMI-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
CACTVS 3.341
OpenEye OEToolkits 1.5.0		[N-]=[N+]=[N-]
FormulaN3
NameAZIDE ION
ChEMBLCHEMBL79455
DrugBank
ZINC
PDB chain1sz6 Chain A Residue 4004 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB1sz6 Crystal Structure of Viscum album Mistletoe Lectin I in native state at 2.05 A resolution, comparison of structure active site conformation in ricin and in viscumin
Resolution2.05 Å
Binding residue
(original residue number in PDB)		D211 N232
Binding residue
(residue number reindexed from 1)		D211 N232
Annotation score1
Enzymatic activity
Catalytic site (original residue number in PDB) V77 E165 R168
Catalytic site (residue number reindexed from 1) V77 E165 R168
Enzyme Commision number 3.2.2.22: rRNA N-glycosylase.
Gene Ontology
Molecular Function
GO:0030598 rRNA N-glycosylase activity
Biological Process
GO:0017148 negative regulation of translation

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Molecular Function
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Biological Process
External links
PDB RCSB:1sz6, PDBe:1sz6, PDBj:1sz6
PDBsum1sz6
PubMed
UniProtP81446|ML1_VISAL Beta-galactoside-specific lectin 1

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