Structure of PDB 1sys Chain A Binding Site BS01

Receptor Information
>1sys Chain A (length=276) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GSHSMRYFYTAMSRPGRGEPRFITVGYVDDTLFVRFDSDATSPRKEPRAP
WIEQEGPEYWDRETQISKTNTQTYRENLRTALRYYNQSEAGSHIIQRMYG
CDVGPDGRLLRGYDQDAYDGKDYIALNEDLSSWTAADTAAQITQRKWEAA
RVAEQLRAYLEGLCVESLRRYLENGKETLQRADPPKTHVTHHPISDHEVT
LRCWALGFYPAEITLTWQRDGEDQTQDTELVETRPAGDRTFQKWAAVVVP
SGEEQRYTCHVQHEGLPKPLTLRWEP
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB1sys Natural HLA class I polymorphism controls the pathway of antigen presentation and susceptibility to viral evasion
Resolution2.4 Å
Binding residue
(original residue number in PDB)
Y7 Y9 K45 E63 I66 E76 N77 Y84 I95 R97 Y99 D114 D116 Y123 T143 K146 W147 Q155 Y159 L163 R170 Y171
Binding residue
(residue number reindexed from 1)
Y7 Y9 K45 E63 I66 E76 N77 Y84 I95 R97 Y99 D114 D116 Y123 T143 K146 W147 Q155 Y159 L163 R170 Y171
Enzymatic activity
Enzyme Commision number ?
External links
PDB RCSB:1sys, PDBe:1sys, PDBj:1sys
PDBsum1sys
PubMed15226359
UniProtP01889|HLAB_HUMAN HLA class I histocompatibility antigen, B alpha chain (Gene Name=HLA-B)

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