Structure of PDB 1svm Chain A Binding Site BS01

Receptor Information
>1svm Chain A (length=362) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
KQVSWKLVTEYAMETKCDDVLLLLGMYLEFQYSFEMCLKCIKKEQPSHYK
YHEKHYANAAIFADSKNQKTICQQAVDTVLAKKRVDSLQLTREQMLTNRF
NDLLDRMDIMFGSTGSADIEEWMAGVAWLHCLLPKMDSVVYDFLKCMVYN
IPKKRYWLFKGPIDSGKTTLAAALLELCGGKALNVNLPLDRLNFELGVAI
DQFLVVFEDVKGTGGESRDLPSGQGINNLDNLRDYLDGSVKVNLEKKHLN
KRTQIFPPGIVTMNEYSVPKTLQARFVKQIDFRPKDYLKHCLERSEFLLE
KRIIQSGIALLLMLIWYRPVAEFAQSIQSRIVEWKERLDKEFSLSVYQKM
KFNVAMGIGVLD
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain1svm Chain A Residue 700 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB1svm Mechanisms of conformational change for a replicative hexameric helicase of SV40 large tumor antigen.
Resolution1.94 Å
Binding residue
(original residue number in PDB)		C302 C305 H313 H317
Binding residue
(residue number reindexed from 1)		C37 C40 H48 H52
Annotation score1
Enzymatic activity
Enzyme Commision number 3.6.4.-
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0005524 ATP binding
Biological Process
GO:0006260 DNA replication

View graph for
Molecular Function
View graph for
Biological Process
External links
PDB RCSB:1svm, PDBe:1svm, PDBj:1svm
PDBsum1svm
PubMed15454080
UniProtP03070|LT_SV40 Large T antigen

[Back to BioLiP]