Structure of PDB 1sua Chain A Binding Site BS01

Receptor Information
>1sua Chain A (length=263) Species: 1390 (Bacillus amyloliquefaciens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
VPYGVSQIKAPALHSQGYTGSNVKVAVIDSGIDSSHPDLNVAGGASFVPS
ETNPFQDNNSHGTHVAGTVLAVAPSASLYAVKVLGADGSGQYSWIINGIE
WAIANNMDVINMSLGGPSGSAALKAAVDKAVASGVVVVAAAGNEGTSGSS
STVGYPGKYPSVIAVGAVDSSNQRASFSSVGPELDVMAPGVSIVSTLPGN
KYGAKSGTAMASPHVAGAAALILSKHPNWTNTQVRSSLENTTTKLGDSFY
YGKGLINVEAAAQ
Ligand information
Receptor-Ligand Complex Structure
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PDB1sua Crystal structure of calcium-independent subtilisin BPN' with restored thermal stability folded without the prodomain.
Resolution2.1 Å
Binding residue
(original residue number in PDB)		H64 G100 S101 G102 Y104 S125 L126 G127 G154 N155 A221
Binding residue
(residue number reindexed from 1)		H61 G88 S89 G90 Y92 S113 L114 G115 G142 N143 A209
Enzymatic activity
Catalytic site (original residue number in PDB) D32 H64 N155 A221
Catalytic site (residue number reindexed from 1) D29 H61 N143 A209
Enzyme Commision number 3.4.21.62: subtilisin.
Gene Ontology
Molecular Function
GO:0004252 serine-type endopeptidase activity
GO:0008236 serine-type peptidase activity
Biological Process
GO:0006508 proteolysis

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Molecular Function
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Biological Process
External links
PDB RCSB:1sua, PDBe:1sua, PDBj:1sua
PDBsum1sua
PubMed9552156
UniProtP00782|SUBT_BACAM Subtilisin BPN' (Gene Name=apr)

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