Structure of PDB 1srh Chain A Binding Site BS01

Receptor Information
>1srh Chain A (length=116) Species: 1895 (Streptomyces avidinii) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
AGITGTWYNQLGSTFIVTAGADGALTGTYESAVGNAESRYVLTGRYDSAP
ASGTALGWTVAWKNNYRNAHSATTWSGQYVGGAEARINTQWLLTSGTTEA
NAWKSTLVGHDTFTKV
Ligand information
Ligand IDMOB
InChIInChI=1S/C15H14N2O5/c1-21-12-7-9(8-13(22-2)14(12)18)16-17-11-6-4-3-5-10(11)15(19)20/h3-8,18H,1-2H3,(H,19,20)/b17-16+
InChIKeyOUUSCQGLQHBVJX-WUKNDPDISA-N
SMILES
SoftwareSMILES
ACDLabs 10.04O=C(O)c2ccccc2/N=N/c1cc(OC)c(O)c(OC)c1
OpenEye OEToolkits 1.5.0COc1cc(cc(c1O)OC)N=Nc2ccccc2C(=O)O
CACTVS 3.341COc1cc(cc(OC)c1O)N=Nc2ccccc2C(O)=O
FormulaC15 H14 N2 O5
Name2-((3',5'-DIMETHOXY-4'-HYDROXYPHENYL)AZO)BENZOIC ACID
ChEMBL
DrugBankDB08196
ZINCZINC000038311600
PDB chain1srh Chain B Residue 300 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB1srh Structural Origins of High-Affinity Biotin Binding to Streptavidin
Resolution2.2 Å
Binding residue
(original residue number in PDB)		S27 Y43 S45 V47 G48 N49 A50 W79 A86 S88 T90 W108
Binding residue
(residue number reindexed from 1)		S13 Y29 S31 V33 G34 N35 A36 W62 A69 S71 T73 W91
Annotation score1
Enzymatic activity
Enzyme Commision number ?
Gene Ontology

View graph for
Molecular Function
External links
PDB RCSB:1srh, PDBe:1srh, PDBj:1srh
PDBsum1srh
PubMed
UniProtP22629|SAV_STRAV Streptavidin

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