Structure of PDB 1sl7 Chain A Binding Site BS01

Receptor Information
>1sl7 Chain A (length=173) Species: 32570 (Obelia longissima) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
TDFDNPRWIKRHKHMFDFLDINGNGKITLDEIVSKASDDICAKLEATPEQ
TKRHQVCVEAFFRGCGMEYGKEIAFPQFLDGWKQLATSELKKWARNEPTL
IREWGDAVFDIFDKDGSGTITLDEWKAYGKISGISPSQEDCEATFRHCDL
DDSGDLDVDEMTRQHLGFWYTLD
Ligand information
Ligand IDCA
InChIInChI=1S/Ca/q+2
InChIKeyBHPQYMZQTOCNFJ-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Ca++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Ca+2]
FormulaCa
NameCALCIUM ION
ChEMBL
DrugBankDB14577
ZINC
PDB chain1sl7 Chain A Residue 301 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB1sl7 All three Ca2+-binding loops of photoproteins bind calcium ions: The crystal structures of calcium-loaded apo-aequorin and apo-obelin.
Resolution2.2 Å
Binding residue
(original residue number in PDB)		D159 D161 S163 D165 E170
Binding residue
(residue number reindexed from 1)		D149 D151 S153 D155 E160
Annotation score4
Enzymatic activity
Catalytic site (original residue number in PDB) H22 W92 Y138 H175
Catalytic site (residue number reindexed from 1) H12 W82 Y128 H165
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0005509 calcium ion binding
GO:0046872 metal ion binding
Biological Process
GO:0008218 bioluminescence

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Molecular Function
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Biological Process
External links
PDB RCSB:1sl7, PDBe:1sl7, PDBj:1sl7
PDBsum1sl7
PubMed15689515
UniProtQ27709|OBL_OBELO Obelin

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