Structure of PDB 1sk4 Chain A Binding Site BS01

Receptor Information
>1sk4 Chain A (length=163) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
PNIIKRSAWEARETHCPKMNLPAKYVIIIHTAGTSCTVSTDCQTVVRNIQ
SFHMDTRNFCDIGYHFLVGQDGGVYEGVGWHIQGSHTYGFNDIALGIAFI
GYFVEKPPNAAALEAAQDLIQCAVVEGYLTPNYLLMGHSDVVNILSPGQA
LYNIISTWPHFKH
Ligand information
Ligand IDNA
InChIInChI=1S/Na/q+1
InChIKeyFKNQFGJONOIPTF-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
CACTVS 3.341
OpenEye OEToolkits 1.5.0		[Na+]
FormulaNa
NameSODIUM ION
ChEMBL
DrugBankDB14516
ZINC
PDB chain1sk4 Chain A Residue 342 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB1sk4 Crystal structure of the C-terminal peptidoglycan-binding domain of human peptidoglycan recognition protein Ialpha
Resolution1.65 Å
Binding residue
(original residue number in PDB)		S317 D318 V319 V320 I322 S324 Q327
Binding residue
(residue number reindexed from 1)		S139 D140 V141 V142 I144 S146 Q149
Annotation score3
Enzymatic activity
Catalytic site (original residue number in PDB) Y242
Catalytic site (residue number reindexed from 1) Y64
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0008270 zinc ion binding
GO:0008745 N-acetylmuramoyl-L-alanine amidase activity
GO:0042834 peptidoglycan binding
Biological Process
GO:0009253 peptidoglycan catabolic process
GO:0045087 innate immune response

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Molecular Function
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Biological Process
External links
PDB RCSB:1sk4, PDBe:1sk4, PDBj:1sk4
PDBsum1sk4
PubMed15140887
UniProtQ96LB9|PGRP3_HUMAN Peptidoglycan recognition protein 3 (Gene Name=PGLYRP3)

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