Structure of PDB 1s8n Chain A Binding Site BS01

Receptor Information

>1s8n Chain A (length=190) Species: 83332 (Mycobacterium tuberculosis H37Rv) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

AVPRRVLIAEDEALIRMDLAEMLREEGYEIVGEAGDGQEAVELAELHKPD
LVIMDVKMPRRDGIDAASEIASKRIAPIVVLTAFSQRDLVERARDAGAMA
YLVKPFSISDLIPAIELAVSRFREITALEGEVATLSERLETRKLVERAKG
LLQTKHGMTEPDAFKWIQRAAMDRRTTMKRVAEVVLETLG

Ligand information

Ligand ID

AZI

InChI

InChI=1S/N3/c1-3-2/q-1

InChIKey

IVRMZWNICZWHMI-UHFFFAOYSA-N

SMILES

Software	SMILES
ACDLabs 10.04 CACTVS 3.341 OpenEye OEToolkits 1.5.0	[N-]=[N+]=[N-]

Formula

Name

AZIDE ION

PDB chain

1s8n Chain A Residue 401 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

Receptor-Ligand Complex Structure

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Structure summary

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PDB	1s8n The Crystal and Solution Structure of a Putative Transcriptional Antiterminator from Mycobacterium tuberculosis.
Resolution	1.482 Å
Binding residue (original residue number in PDB)	E141 A181 M182 T186
Binding residue (residue number reindexed from 1)	E131 A171 M172 T176
Annotation score	1

Enzymatic activity

Enzyme Commision number

Gene Ontology

	Molecular Function
GO:0003723	RNA binding
GO:0043168	anion binding

	Biological Process
GO:0000160	phosphorelay signal transduction system
GO:0031564	transcription antitermination

	Cellular Component
GO:0005737	cytoplasm
GO:0005886	plasma membrane
GO:0009274	peptidoglycan-based cell wall

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Cellular Component

External links

PDB	RCSB:1s8n, PDBe:1s8n, PDBj:1s8n
PDBsum	1s8n
PubMed	15341725
UniProt	P9WGM3\|PDTAR_MYCTU Transcriptional regulatory protein PdtaR (Gene Name=pdtaR)

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