Structure of PDB 1s8d Chain A Binding Site BS01

Receptor Information
>1s8d Chain A (length=275) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GSHSMRYFFTSVSRPGRGEPRFIAVGYVDDTQFVRFDSDAASQRMEPRAP
WIEQEGPEYWDGETRKVKAHSQTHRVDLGTLRGYYNQSEAGSHTVQRMYG
CDVGSDWRFLRGYHQYAYDGKDYIALKEDLRSWTAADMAAQTTKHKWEAA
HVAEQLRAYLEGTCVEWLRRYLENGKETLQRTDAPKTHMTHHAVSDHEAT
LRCWALSFYPAEITLTWQRDGEDQTQDTELVETRPAGDGTFQKWAAVVVP
SGQEQRYTCHVQHEGLPKPLTLRWE
Ligand information
>1s8d Chain C (length=9) Species: 11676 (Human immunodeficiency virus 1) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
SLANTVATL
Receptor-Ligand Complex Structure
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PDB1s8d Structural Basis for Degenerate Recognition of Natural HIV Peptide Variants by Cytotoxic Lymphocytes.
Resolution2.2 Å
Binding residue
(original residue number in PDB)
Y7 E63 K66 V67 H70 D77 L81 R97 Y99 Y116 T143 K146 W147 Y159 W167 Y171
Binding residue
(residue number reindexed from 1)
Y7 E63 K66 V67 H70 D77 L81 R97 Y99 Y116 T143 K146 W147 Y159 W167 Y171
Enzymatic activity
Enzyme Commision number ?
External links
PDB RCSB:1s8d, PDBe:1s8d, PDBj:1s8d
PDBsum1s8d
PubMed16702212
UniProtP04439|HLAA_HUMAN HLA class I histocompatibility antigen, A alpha chain (Gene Name=HLA-A)

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