Structure of PDB 1s69 Chain A Binding Site BS01

Receptor Information

>1s69 Chain A (length=123) Species: 1148 (Synechocystis sp. PCC 6803)

STLYEKLGGTTAVDLAVDKFYERVLQDDRIKHFFADVDMAKQRAHQKAFL
TYAFGGTDKYDGRYMREAHKELVENHGLNGEHFDAVAEDLLATLKEMGVP
EDLIAEVAAVAGAPAHKRDVLNQ

Ligand information

• Ligand ID: CYN
• InChI: InChI=1S/CN/c1-2/q-1
• InChIKey: XFXPMWWXUTWYJX-UHFFFAOYSA-N
• SMILES:
  ACDLabs 10.04
  CACTVS 3.341
  OpenEye OEToolkits 1.5.0: [C-]#N
• Formula: C N
• Name: CYANIDE ION
• PDB chain: 1s69 Chain A Residue 126

Receptor-Ligand Complex Structure

Structure summary

• PDB: 1s69 Crystallographic analysis of synechocystis cyanoglobin reveals the structural changes accompanying ligand binding in a hexacoordinate hemoglobin.
• Resolution: 1.68 Å
• Binding residue (original residue number in PDB): Y22 Q43 Q47
• Binding residue (residue number reindexed from 1): Y21 Q42 Q46
• Annotation score: 1

Gene Ontology

Molecular Function

• GO:0005344 oxygen carrier activity
• GO:0008379 thioredoxin peroxidase activity
• GO:0019825 oxygen binding
• GO:0020037 heme binding
• GO:0046872 metal ion binding

Biological Process

• GO:0015671 oxygen transport
• GO:0034599 cellular response to oxidative stress
• GO:0045454 cell redox homeostasis
• GO:0098869 cellular oxidant detoxification

Cellular Component

• GO:0005737 cytoplasm

External links

• PDB: RCSB:1s69, PDBe:1s69, PDBj:1s69
• PDBsum: 1s69
• PubMed: 15289104
• UniProt: P73925|TRHBN_SYNY3 Group 1 truncated hemoglobin GlbN (Gene Name=glbN)