Structure of PDB 1rro Chain A Binding Site BS01

Receptor Information

>1rro Chain A (length=108) Species: 10117 (Rattus rattus)

SITDILSAEDIAAALQECQDPDTFEPQKFFQTSGLSKMSASQVKDIFRFI
DNDQSGYLDGDELKYFLQKFQSDARELTESETKSLMDAADNDGDGKIGAD
EFQEMVHS

Ligand information

• Ligand ID: CA
• InChI: InChI=1S/Ca/q+2
• InChIKey: BHPQYMZQTOCNFJ-UHFFFAOYSA-N
• SMILES:
  CACTVS 3.341: [Ca++]
  ACDLabs 10.04
  OpenEye OEToolkits 1.5.0: [Ca+2]
• Formula: Ca
• Name: CALCIUM ION
• DrugBank: DB14577
• PDB chain: 1rro Chain A Residue 109

Receptor-Ligand Complex Structure

Structure summary

• PDB: 1rro Refinement of recombinant oncomodulin at 1.30 A resolution.
• Resolution: 1.3 Å
• Binding residue (original residue number in PDB): D90 D92 D94 K96 E101
• Binding residue (residue number reindexed from 1): D90 D92 D94 K96 E101
• Annotation score: 4

Gene Ontology

Molecular Function

• GO:0005509 calcium ion binding
• GO:0042802 identical protein binding
• GO:0042803 protein homodimerization activity
• GO:0044877 protein-containing complex binding
• GO:0046872 metal ion binding

Biological Process

• GO:0009611 response to wounding
• GO:0090102 cochlea development

Cellular Component

• GO:0005615 extracellular space
• GO:0005737 cytoplasm
• GO:0031982 vesicle
• GO:0032420 stereocilium
• GO:0032437 cuticular plate
• GO:0032991 protein-containing complex
• GO:0099512 supramolecular fiber

External links

• PDB: RCSB:1rro, PDBe:1rro, PDBj:1rro
• PDBsum: 1rro
• PubMed: 8487302
• UniProt: P02631|ONCO_RAT Oncomodulin (Gene Name=Ocm)