Structure of PDB 1rrc Chain A Binding Site BS01

Receptor Information
>1rrc Chain A (length=288) Species: 10665 (Tequatrovirus T4) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MKKIILTIGCPGSGKSTWAREFIAKNPGFYNINRDDYRQSIMAHEERDEY
KYTKKKEGIVTGMQFDTAKSILYGGDSVKGVIISDTNLNPERRLAWETFA
KEYGWKVEHKVFDVPWTELVKRNSKRGTKAVPIDVLRSMYKSMREYLGLP
VYNGTPGKPKAVIFDVDGTLAKMDVINPMVVELSKMYALMGYQIVVVSGR
ESGTKEDPTKYYRMTRKWVEDIAGVPLVMQCQREQGDTRKDDVVKEEIFW
KHIAPHFDVKLAIDDRTQVVEMWRRIGVECWQVASGDF
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB1rrc Recognition of DNA substrates by T4 bacteriophage polynucleotide kinase.
Resolution2.46 Å
Binding residue
(original residue number in PDB)		R34 D35 R38 Y52 E57 T61 T86 V131 P132 V135
Binding residue
(residue number reindexed from 1)		R34 D35 R38 Y52 E57 T61 T86 V131 P132 V135
Enzymatic activity
Catalytic site (original residue number in PDB) K15 D35 R126 D165
Catalytic site (residue number reindexed from 1) K15 D35 R126 D165
Enzyme Commision number 2.7.1.78: polynucleotide 5'-hydroxyl-kinase.
3.1.3.34: deoxynucleotide 3'-phosphatase.
Gene Ontology
Molecular Function
GO:0005524 ATP binding
GO:0016301 kinase activity
GO:0016787 hydrolase activity
GO:0046404 ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity
GO:0047846 deoxynucleotide 3'-phosphatase activity
GO:0051734 ATP-dependent polynucleotide 5'-hydroxyl-kinase activity
Biological Process
GO:0006281 DNA repair
GO:0016310 phosphorylation

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Molecular Function
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Biological Process
External links
PDB RCSB:1rrc, PDBe:1rrc, PDBj:1rrc
PDBsum1rrc
PubMed14754987
UniProtP06855|KIPN_BPT4 Polynucleotide kinase (Gene Name=pseT)

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