Structure of PDB 1ro5 Chain A Binding Site BS01

Receptor Information
>1ro5 Chain A (length=197) Species: 287 (Pseudomonas aeruginosa) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GSHMIVQIGRREEFDKKLLGEMHKLRAQVFKERKGWDVSVIDEMEIDGYD
ALSPYYMLIQEDGQVFGCWRILDTTGPYMLKNTFPELLHGKEAPCSPHIW
ELSRFAINSGQKGSLGFSDCTLEAMRALARYSLQNDIQTLVTVTTVGVEK
MMIRAGLDVSRFGPHLKIGIERAVALRIELNAKTQIALYGGVLVEQR
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain1ro5 Chain A Residue 405 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB1ro5 Structure of the Pseudomonas aeruginosa acyl-homoserinelactone synthase LasI.
Resolution2.3 Å
Binding residue
(original residue number in PDB)		G397 S398 H399
Binding residue
(residue number reindexed from 1)		G1 S2 H3
Annotation score1
Enzymatic activity
Enzyme Commision number 2.3.1.184: acyl-homoserine-lactone synthase.
Gene Ontology
Molecular Function
GO:0016740 transferase activity

View graph for
Molecular Function
External links
PDB RCSB:1ro5, PDBe:1ro5, PDBj:1ro5
PDBsum1ro5
PubMed15306017
UniProtP33883|LASI_PSEAE Acyl-homoserine-lactone synthase (Gene Name=lasI)

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