Structure of PDB 1rlo Chain A Binding Site BS01

Receptor Information
>1rlo Chain A (length=268) Species: 562 (Escherichia coli) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
VKVIVTDMDGTFLNDAKTYNQPRFMAQYQELKKRGIKFVVASGNQYYQLI
SFFPELKDEISFVAENGALVYEHGKQLFHGELTRHESRIVIGELLKDKQL
NFVACGLQSAYVSENAPEAFVALMAKHYHRLKPVKDYQEIDDVLFKFSLN
LPDEQIPLVIDKLHVALDGIMKPVTSGFGFIDLIIPGLHKANGISRLLKR
WDLSPQNVVAIGDSGNDAEMLKMARYSFAMGNAAENIKQIARYATDDNNH
EGALNVIQAVLDNTYPFN
Ligand information
Ligand IDMG
InChIInChI=1S/Mg/q+2
InChIKeyJLVVSXFLKOJNIY-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Mg+2]
CACTVS 3.341[Mg++]
FormulaMg
NameMAGNESIUM ION
ChEMBL
DrugBankDB01378
ZINC
PDB chain1rlo Chain A Residue 801 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB1rlo Ybiv from Escherichia coli K12 is a HAD phosphatase.
Resolution2.0 Å
Binding residue
(original residue number in PDB)		X9 D11 D215
Binding residue
(residue number reindexed from 1)		X7 D9 D213
Annotation score1
Enzymatic activity
Enzyme Commision number 3.1.3.23: sugar-phosphatase.
Gene Ontology
Molecular Function
GO:0000287 magnesium ion binding
GO:0016787 hydrolase activity
GO:0016791 phosphatase activity
GO:0046872 metal ion binding
GO:0050286 sorbitol-6-phosphatase activity
GO:0050308 sugar-phosphatase activity
GO:0103026 fructose-1-phosphatase activity
Cellular Component
GO:0005829 cytosol

View graph for
Molecular Function
View graph for
Cellular Component
External links
PDB RCSB:1rlo, PDBe:1rlo, PDBj:1rlo
PDBsum1rlo
PubMed15657928
UniProtP75792|SUPH_ECOLI Sugar phosphatase YbiV (Gene Name=ybiV)

[Back to BioLiP]