Structure of PDB 1rks Chain A Binding Site BS01
Receptor Information
>1rks Chain A (length=305) Species:
562
(Escherichia coli) [
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AGSLVVLGSINADHILNLQSFPTPGETVTGNHYQVAFGGKGANQAVAAGR
SGANIAFIACTGDDSIGESVRQQLATDNIDITPVSVIKGESTGVALIFVN
GEGENVIGIHAGANAALSPALVEAQRERIANASALLMQLESPLESVMAAA
KIAHQNKTIVALNPAPARELPDELLALVDIITPNETEAEKLTGIRVENDE
DAAKAAQVLHEKGIRTVLITLGSRGVWASVNGEGQRVPGFRVQAVDTIAA
GDTFNGALITALLEEKPLPEAIRFAHAAAAIAVTRKGAQPSVPWREEIDA
FLDRQ
Ligand information
Ligand ID
RIB
InChI
InChI=1S/C5H10O5/c6-1-2-3(7)4(8)5(9)10-2/h2-9H,1H2/t2-,3-,4-,5+/m1/s1
InChIKey
HMFHBZSHGGEWLO-AIHAYLRMSA-N
SMILES
Software
SMILES
OpenEye OEToolkits 1.5.0
C(C1C(C(C(O1)O)O)O)O
CACTVS 3.341
OC[CH]1O[CH](O)[CH](O)[CH]1O
CACTVS 3.341
OC[C@H]1O[C@H](O)[C@H](O)[C@@H]1O
OpenEye OEToolkits 1.5.0
C([C@@H]1[C@H]([C@H]([C@H](O1)O)O)O)O
ACDLabs 10.04
OC1C(OC(O)C1O)CO
Formula
C5 H10 O5
Name
alpha-D-ribofuranose;
alpha-D-ribose;
D-ribose;
ribose
ChEMBL
CHEMBL606078
DrugBank
ZINC
ZINC000003860714
PDB chain
1rks Chain A Residue 311 [
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Receptor-Ligand Complex Structure
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PDB
1rks
Induced fit on sugar binding activates ribokinase.
Resolution
2.4 Å
Binding residue
(original residue number in PDB)
N14 D16 G42 K43 N46 A98 E143 D255
Binding residue
(residue number reindexed from 1)
N11 D13 G39 K40 N43 A95 E140 D252
Annotation score
5
Enzymatic activity
Catalytic site (original residue number in PDB)
A252 A253 G254 D255
Catalytic site (residue number reindexed from 1)
A249 A250 G251 D252
Enzyme Commision number
2.7.1.15
: ribokinase.
Gene Ontology
Molecular Function
GO:0004747
ribokinase activity
GO:0005524
ATP binding
GO:0016301
kinase activity
GO:0042803
protein homodimerization activity
GO:0046872
metal ion binding
Biological Process
GO:0006014
D-ribose metabolic process
GO:0016310
phosphorylation
GO:0019303
D-ribose catabolic process
GO:0046835
carbohydrate phosphorylation
Cellular Component
GO:0005737
cytoplasm
GO:0005829
cytosol
View graph for
Molecular Function
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Biological Process
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Cellular Component
External links
PDB
RCSB:1rks
,
PDBe:1rks
,
PDBj:1rks
PDBsum
1rks
PubMed
10438599
UniProt
P0A9J6
|RBSK_ECOLI Ribokinase (Gene Name=rbsK)
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