Structure of PDB 1ram Chain A Binding Site BS01

Receptor Information
>1ram Chain A (length=273) Species: 10090 (Mus musculus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
PYVEIIEQPKQRGMRFRYKCEGRSAGSIPGERSTDTTKTHPTIKINGYTG
PGTVRISLVTKDPPHRPHPHELVGKDCRDGYYEADLCPDRSIHSFQNLGI
QCVKKRDLEQAISQRIQTNNNPFHVPIEEQRGDYDLNAVRLCFQVTVRDP
AGRPLLLTPVLSHPIFDNRAPNTAELKICRVNRNSGSCLGGDEIFLLCDK
VQKEDIEVYFTGPGWEARGSFSQADVHRQVAIVFRTPPYADPSLQAPVRV
SMQLRRPSDRELSEPMEFQYLPD
Ligand information
Receptor-Ligand Complex Structure
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PDB1ram A novel DNA recognition mode by the NF-kappa B p65 homodimer.
Resolution2.7 Å
Binding residue
(original residue number in PDB)		Y36 C38 K122 K123 R187 K218 R246 Q247
Binding residue
(residue number reindexed from 1)		Y18 C20 K104 K105 R169 K200 R228 Q229
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0003700 DNA-binding transcription factor activity
Biological Process
GO:0006355 regulation of DNA-templated transcription
Cellular Component
GO:0005737 cytoplasm

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:1ram, PDBe:1ram, PDBj:1ram
PDBsum1ram
PubMed9437432
UniProtQ04207|TF65_MOUSE Transcription factor p65 (Gene Name=Rela)

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