Structure of PDB 1r9p Chain A Binding Site BS01

Receptor Information
>1r9p Chain A (length=134) Species: 727 (Haemophilus influenzae) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MAYSEKVIDHYENPRNVGSLDKKDSNVGTGMVGAPACGDVMQLQIKVDDN
GIIEDAKFKTYGCGSAIASSSLITEWVKGKSLEEAGAIKNSQIAEELELP
PVKVHCSILAEDAIKAAIADYKAKQGLEHHHHHH
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain1r9p Chain A Residue 135 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB1r9p Solution NMR structure of the iron-sulfur cluster assembly protein U (IscU) with zinc bound at the active site.
ResolutionN/A
Binding residue
(original residue number in PDB)		C37 C63 H105
Binding residue
(residue number reindexed from 1)		C37 C63 H105
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0005506 iron ion binding
GO:0008198 ferrous iron binding
GO:0046872 metal ion binding
GO:0051536 iron-sulfur cluster binding
GO:0051537 2 iron, 2 sulfur cluster binding
Biological Process
GO:0006879 intracellular iron ion homeostasis
GO:0016226 iron-sulfur cluster assembly
Cellular Component
GO:0005737 cytoplasm

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:1r9p, PDBe:1r9p, PDBj:1r9p
PDBsum1r9p
PubMed15522305
UniProtQ57074|ISCU_HAEIN Iron-sulfur cluster assembly scaffold protein IscU (Gene Name=iscU)

[Back to BioLiP]