Structure of PDB 1r8e Chain A Binding Site BS01

Receptor Information
>1r8e Chain A (length=275) Species: 1423 (Bacillus subtilis) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
ESYYSIGEVSKLANVSIKALRYYDKIDLFKPAYVDPDTSYRYYTDSQLIH
LDLIKSLKYIGTPLEEMKKAQDLEMEELFAFYTEQERQIREKLDFLSALE
QTISLVKKRMKRQMEYPALGEVFVLDEEEIRIIQTEAEGIGPENVLNASY
SKLKKFIESADGFTNNSYGATFSFQPYTSIDEMTYRHIFTPVLTNKQISS
ITPDMEITTIPKGRYACIAYNFSPEHYFLNLQKLIKYIADRQLTVVSDVY
ELIIPIHYSPKKQEEYRVEMKIRIA
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB1r8e The structural mechanism for transcription activation by MerR family member multidrug transporter activation, N terminus.
Resolution2.4 Å
Binding residue
(original residue number in PDB)		S7 I8 G9 R23 Y42 R43
Binding residue
(residue number reindexed from 1)		S5 I6 G7 R21 Y40 R41
Binding affinityPDBbind-CN: Kd=2.4nM
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0003700 DNA-binding transcription factor activity
Biological Process
GO:0006355 regulation of DNA-templated transcription

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Molecular Function
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Biological Process
External links
PDB RCSB:1r8e, PDBe:1r8e, PDBj:1r8e
PDBsum1r8e
PubMed14985361
UniProtP39075|BMRR_BACSU Multidrug-efflux transporter 1 regulator (Gene Name=bmrR)

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