Structure of PDB 1r03 Chain A Binding Site BS01

Receptor Information
>1r03 Chain A (length=171) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SRVRQNFHPDSEAAINRQINLELYASYVYLSMAYYFSRDDVALNNFSRYF
LHQSREETEHAEKLMRLQNQRGGRIRLQDIKKPEQDDWESGLHAMECALL
LEKNVNQSLLELHALASDKGDPHLCDFLETYYLNEQVKSIKELGDHVHNL
VKMGAPDAGLAEYLFDTHTLG
Ligand information
Ligand IDMG
InChIInChI=1S/Mg/q+2
InChIKeyJLVVSXFLKOJNIY-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Mg+2]
CACTVS 3.341[Mg++]
FormulaMg
NameMAGNESIUM ION
ChEMBL
DrugBankDB01378
ZINC
PDB chain1r03 Chain A Residue 301 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB1r03 Crystal Structure and Biochemical Properties of the Human Mitochondrial Ferritin and its Mutant Ser144Ala
Resolution1.7 Å
Binding residue
(original residue number in PDB)		E27 E62 H65
Binding residue
(residue number reindexed from 1)		E22 E57 H60
Annotation score1
Enzymatic activity
Enzyme Commision number 1.16.3.1: ferroxidase.
Gene Ontology
Molecular Function
GO:0008199 ferric iron binding
Biological Process
GO:0006826 iron ion transport
GO:0006879 intracellular iron ion homeostasis

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Molecular Function
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Biological Process
External links
PDB RCSB:1r03, PDBe:1r03, PDBj:1r03
PDBsum1r03
PubMed15201052
UniProtQ8N4E7|FTMT_HUMAN Ferritin, mitochondrial (Gene Name=FTMT)

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