Structure of PDB 1qtk Chain A Binding Site BS01

Receptor Information

>1qtk Chain A (length=129) Species: 9031 (Gallus gallus)

KVFGRCELAAAMKRHGLDNYRGYSLGNWVCAAKFESNFNTQATNRNTDGS
TDYGILQINSRWWCNDGRTPGSRNLCNIPCSALLSSDITASVNCAKKIVS
DGNGMNAWVAWRNRCKGTDVQAWIRGCRL

Ligand information

• Ligand ID: KR
• InChI: InChI=1S/Kr
• InChIKey: DNNSSWSSYDEUBZ-UHFFFAOYSA-N
• SMILES:
  ACDLabs 10.04
  CACTVS 3.341
  OpenEye OEToolkits 1.5.0: [Kr]
• Formula: Kr
• Name: KRYPTON
• ChEMBL: CHEMBL1233877
• PDB chain: 1qtk Chain A Residue 150

Receptor-Ligand Complex Structure

Structure summary

• PDB: 1qtk Exploring hydrophobic sites in proteins with xenon or krypton.
• Resolution: 2.03 Å
• Binding residue (original residue number in PDB): L56 S91 V92
• Binding residue (residue number reindexed from 1): L56 S91 V92
• Annotation score: 1

Enzymatic activity

• Catalytic site (original residue number in PDB): E35 N46 D48 S50 D52 N59
• Catalytic site (residue number reindexed from 1): E35 N46 D48 S50 D52 N59
• Enzyme Commision number: 3.2.1.17: lysozyme.

Gene Ontology

Molecular Function

• GO:0003796 lysozyme activity
• GO:0005515 protein binding
• GO:0016231 beta-N-acetylglucosaminidase activity
• GO:0016798 hydrolase activity, acting on glycosyl bonds
• GO:0042802 identical protein binding

Biological Process

• GO:0016998 cell wall macromolecule catabolic process
• GO:0031640 killing of cells of another organism
• GO:0042742 defense response to bacterium
• GO:0050829 defense response to Gram-negative bacterium
• GO:0050830 defense response to Gram-positive bacterium

Cellular Component

• GO:0005576 extracellular region
• GO:0005615 extracellular space
• GO:0005737 cytoplasm
• GO:0005783 endoplasmic reticulum

External links

• PDB: RCSB:1qtk, PDBe:1qtk, PDBj:1qtk
• PDBsum: 1qtk
• PubMed: 9443341
• UniProt: P00698|LYSC_CHICK Lysozyme C (Gene Name=LYZ)