Structure of PDB 1qt1 Chain A Binding Site BS01

Receptor Information

>1qt1 Chain A (length=387) Species: 1956 (Streptomyces diastaticus)

SYQPTPEDKFTFGLWTVGWQGRDPFGDATRGALDPAESVRRLAELGAHGV
TFHDDDLIPFGATDSERAEHIKRFRQGLDETGMKVPMATTNLFTHPVFKD
GGFTANDRDVRRYALRKTIRNIDLAVELGAQTYVAWGGREGAESGAAKDV
RVALDRMKEAFDLLGEYVTSQGYDTPFAIEPKPNEPRGDILLPTIGHALA
FIDGLERPELYGVNPEVGHEQMAGLNFPHGIAQALWAGKLFHIDLNGQSG
IKYDQDLRFGPGDLRAAFWLVDLLESAGYEGPRHFDFKPPRTEDFDGVWA
SAAGCMRNYLILKERAAAFRADPEVQEALRAARLDELAQPTAGDGLQALL
PDRSAFEDFDPDAAAARGMAFERLDQLAMDHLLGARG

Ligand information

• Ligand ID: CO
• InChI: InChI=1S/Co/q+2
• InChIKey: XLJKHNWPARRRJB-UHFFFAOYSA-N
• SMILES:
  ACDLabs 10.04
  OpenEye OEToolkits 1.5.0: [Co+2]
  CACTVS 3.341: [Co++]
• Formula: Co
• Name: COBALT (II) ION
• DrugBank: DB14205
• PDB chain: 1qt1 Chain A Residue 400

Receptor-Ligand Complex Structure

Structure summary

• PDB: 1qt1 Structure of xylose isomerase from Streptomyces diastaticus no. 7 strain M1033 at 1.85 A resolution.
• Resolution: 1.85 Å
• Binding residue (original residue number in PDB): E180 E216 D244 D286
• Binding residue (residue number reindexed from 1): E180 E216 D244 D286
• Annotation score: 1

Enzymatic activity

• Catalytic site (original residue number in PDB): M87
• Catalytic site (residue number reindexed from 1): M87
• Enzyme Commision number: 5.3.1.5: xylose isomerase.

Gene Ontology

Molecular Function

• GO:0000287 magnesium ion binding
• GO:0009045 xylose isomerase activity
• GO:0016853 isomerase activity
• GO:0046872 metal ion binding

Biological Process

• GO:0005975 carbohydrate metabolic process
• GO:0042732 D-xylose metabolic process

Cellular Component

• GO:0005737 cytoplasm

External links

• PDB: RCSB:1qt1, PDBe:1qt1, PDBj:1qt1
• PDBsum: 1qt1
• PubMed: 10666592
• UniProt: P50910|XYLA_STRDI Xylose isomerase (Gene Name=xylA)