Structure of PDB 1qsf Chain A Binding Site BS01

Receptor Information
>1qsf Chain A (length=274) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GSHSMRYFFTSVSRPGRGEPRFIAVGYVDDTQFVRFDSDAASQRMEPRAP
WIEQEGPEYWDGETRKVKAHSQTHRVDLGTLRGYYNQSEAGSHTVQRMYG
CDVGSDWRFLRGYHQYAYDGKDYIALKEDLRSWTAADMAAQTTKHKWEAA
HVAEQLRAYLEGTCVEWLRRYLENGKETLQRTDAPKTHMTHHAVSDHEAT
LRCWALSFYPAEITLTWQADGEDQTQDTELVETRPAGDGTFQKWAAVVVP
SGQEQRYTCHVQHEGLPKPLTLRW
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB1qsf Four A6-TCR/peptide/HLA-A2 structures that generate very different T cell signals are nearly identical.
Resolution2.8 Å
Binding residue
(original residue number in PDB)
Y7 Y59 E63 K66 V67 T73 D77 L81 Y84 Y99 Y116 T143 K146 W147 L156 Y159 W167 Y171
Binding residue
(residue number reindexed from 1)
Y7 Y59 E63 K66 V67 T73 D77 L81 Y84 Y99 Y116 T143 K146 W147 L156 Y159 W167 Y171
Enzymatic activity
Enzyme Commision number ?
External links
PDB RCSB:1qsf, PDBe:1qsf, PDBj:1qsf
PDBsum1qsf
PubMed10435578
UniProtP04439|HLAA_HUMAN HLA class I histocompatibility antigen, A alpha chain (Gene Name=HLA-A)

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