Structure of PDB 1qs8 Chain A Binding Site BS01

Receptor Information
>1qs8 Chain A (length=327) Species: 5855 (Plasmodium vivax) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SENDVIELDDVANIMFYGEGEVGDNHQKFMLIFDTGSANLWVPSKKCNSS
GCSIKNLYDSSKSKSYEKDGTKVDITYGSGTVKGFFSKDLVTLGHLSMPY
KFIEVIDTDDLEPIYSSVEFDGILGLGWKDLSIGSIDPIVVELKNQNKID
NALFTFYLPVHDVHAGYLTIGGIEEKFYEGNITYEKLNHDLYWQIDLDVH
FGKQTMEKANVIVDSGTTTITAPSEFLNKFFANLNVIKVPFLPFYVTTCD
NKEMPTLEFKSANNTYTLEPEYYMNPILEVDDTLCMITMLPVDIDSNTFI
LGDPFMRKYFTVFDYDKESVGFAIAKN
Ligand information
>1qs8 Chain C (length=6) Species: 285516 (Streptomyces argenteolus subsp. toyonakensis) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
VVVLAL
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB1qs8 Structural insights into the activation of P. vivax plasmepsin.
Resolution2.5 Å
Binding residue
(original residue number in PDB)		D34 G36 T76 Y77 G78 S79 Y192 D214 G216 T217 T218 T219
Binding residue
(residue number reindexed from 1)		D34 G36 T76 Y77 G78 S79 Y192 D214 G216 T217 T218 T219
Enzymatic activity
Catalytic site (original residue number in PDB) D34 S37 N39 W41 Y77 D214 T217
Catalytic site (residue number reindexed from 1) D34 S37 N39 W41 Y77 D214 T217
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0004190 aspartic-type endopeptidase activity
Biological Process
GO:0006508 proteolysis

View graph for
Molecular Function
View graph for
Biological Process
External links
PDB RCSB:1qs8, PDBe:1qs8, PDBj:1qs8
PDBsum1qs8
PubMed12767832
UniProtO60989

[Back to BioLiP]