Structure of PDB 1qgj Chain A Binding Site BS01

Receptor Information

>1qgj Chain A (length=300) Species: 3702 (Arabidopsis thaliana)

QLSPDIYAKSCPNLVQIVRKQVAIALKAEIRMAASLIRLHFHDCFVNGCD
ASLLLDGADSEKLAIPNINSARGFEVIDTIKAAVENACPGVVSCADILTL
AARDSVVLSGGPGWRVALGRKDGLVANQNSANNLPSPFEPLDAIIAKFVA
VNLNITDVVALSGAHTFGQAKCAVFSNRLFNFTGAGNPDATLETSLLSNL
QTVCPLGGNSNITAPLDRSTTDTFDNNYFKNLLEGKGLLSSDQILFSSDL
AVNTTKKLVEAYSRSQSLFFRDFTCAMIRMGNISNGASGEVRTNCRVINN

Ligand information

• Ligand ID: CA
• InChI: InChI=1S/Ca/q+2
• InChIKey: BHPQYMZQTOCNFJ-UHFFFAOYSA-N
• SMILES:
  CACTVS 3.341: [Ca++]
  ACDLabs 10.04
  OpenEye OEToolkits 1.5.0: [Ca+2]
• Formula: Ca
• Name: CALCIUM ION
• DrugBank: DB14577
• PDB chain: 1qgj Chain A Residue 2001

Receptor-Ligand Complex Structure

Structure summary

• PDB: 1qgj Arabidopsis thaliana peroxidase N: structure of a novel neutral peroxidase.
• Resolution: 1.9 Å
• Binding residue (original residue number in PDB): D43 V46 G48 D50 S52
• Binding residue (residue number reindexed from 1): D43 V46 G48 D50 S52
• Annotation score: 1

Enzymatic activity

• Catalytic site (original residue number in PDB): R38 H42 N67 H165
• Catalytic site (residue number reindexed from 1): R38 H42 N67 H165
• Enzyme Commision number: 1.11.1.7: peroxidase.

Gene Ontology

Molecular Function

• GO:0004601 peroxidase activity
• GO:0020037 heme binding
• GO:0046872 metal ion binding
• GO:0140825 lactoperoxidase activity

Biological Process

• GO:0006979 response to oxidative stress
• GO:0042744 hydrogen peroxide catabolic process
• GO:0098869 cellular oxidant detoxification

Cellular Component

• GO:0005576 extracellular region
• GO:0005634 nucleus
• GO:0005737 cytoplasm

External links

• PDB: RCSB:1qgj, PDBe:1qgj, PDBj:1qgj
• PDBsum: 1qgj
• PubMed: 10713531
• UniProt: Q39034|PER59_ARATH Peroxidase 59 (Gene Name=PER59)