Structure of PDB 1qbq Chain A Binding Site BS01

Receptor Information
>1qbq Chain A (length=312) Species: 10116 (Rattus norvegicus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
FLSLDSPTYVLYRDRAEWADIDPVPQNDGPSPVVQIIYSEKFRDVYDYFR
AVLQRDERSERAFKLTRDAIELNAANYTVWHFRRVLLRSLQKDLQEEMNY
ITAIIEEQPKNYQVWHHRRVLVEWLKDPSQELEFIADILNQDAKNYHAWQ
HRQWVIQEFRLWDNELQYVDQLLKEDVRNNSVWNQRHFVISNTTGYSDRA
VLEREVQYTLEMIKLVPHNESAWNYLKGILQDRGLSRYPNLLNQLLDLQP
SHSSPYLIAFLVDIYEDMLENQCDNKEDILNKALELCEILAKEKDTIRKE
YWRYIGRSLQSK
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB1qbq Crystal structure of farnesyl protein transferase complexed with a CaaX peptide and farnesyl diphosphate analogue
Resolution2.4 Å
Binding residue
(original residue number in PDB)		K164 Y166
Binding residue
(residue number reindexed from 1)		K110 Y112
Enzymatic activity
Catalytic site (original residue number in PDB) K164
Catalytic site (residue number reindexed from 1) K110
Enzyme Commision number 2.5.1.58: protein farnesyltransferase.
2.5.1.59: protein geranylgeranyltransferase type I.
Gene Ontology
Molecular Function
GO:0008318 protein prenyltransferase activity
Biological Process
GO:0018342 protein prenylation

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Molecular Function
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Biological Process
External links
PDB RCSB:1qbq, PDBe:1qbq, PDBj:1qbq
PDBsum1qbq
PubMed9843427
UniProtQ04631|FNTA_RAT Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha (Gene Name=Fnta)

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