Structure of PDB 1qbj Chain A Binding Site BS01

Receptor Information
>1qbj Chain A (length=65) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SIYQDQEQRILKFLEELGEGKATTAHDLSGKLGTPKKEINRVLYSLAKKG
KLQKEAGTPPLWKIA
Ligand information
Receptor-Ligand Complex Structure
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PDB1qbj Crystal structure of the Zalpha domain of the human editing enzyme ADAR1 bound to left-handed Z-DNA.
Resolution2.1 Å
Binding residue
(original residue number in PDB)
K169 K170 N173 R174 Y177 T191 P192 P193
Binding residue
(residue number reindexed from 1)
K36 K37 N40 R41 Y44 T58 P59 P60
Enzymatic activity
Enzyme Commision number 3.5.4.37: double-stranded RNA adenine deaminase.
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0003726 double-stranded RNA adenosine deaminase activity

View graph for
Molecular Function
External links
PDB RCSB:1qbj, PDBe:1qbj, PDBj:1qbj
PDBsum1qbj
PubMed10364558
UniProtP55265|DSRAD_HUMAN Double-stranded RNA-specific adenosine deaminase (Gene Name=ADAR)

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