Structure of PDB 1q94 Chain A Binding Site BS01

Receptor Information
>1q94 Chain A (length=275) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GSHSMRYFYTSVSRPGRGEPRFIAVGYVDDTQFVRFDSDAASQRMEPRAP
WIEQEGPEYWDQETRNVKAQSQTDRVDLGTLRGYYNQSEDGSHTIQIMYG
CDVGPDGRFLRGYRQDAYDGKDYIALNEDLRSWTAADMAAQITKRKWEAA
HAAEQQRAYLEGRCVEWLRRYLENGKETLQRTDPPKTHMTHHPISDHEAT
LRCWALGFYPAEITLTWQRDGEDQTQDTELVETRPAGDGTFQKWAAVVVP
SGEEQRYTCHVQHEGLPKPLTLRWE
Ligand information
>1q94 Chain C (length=9) Species: 11683 (Human immunodeficiency virus type 1 (Z2/CDC-Z34 ISOLATE)) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
AIFQSSMTK
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB1q94 Structures of HLA-A*1101 complexed with immunodominant nonamer and decamer HIV-1 epitopes clearly reveal the presence of a middle, secondary anchor residue.
Resolution2.4 Å
Binding residue
(original residue number in PDB)		Y7 Y9 E63 N66 V67 Q70 D77 Y84 Y99 R114 D116 T143 K146 W147 A150 A152 Q155 Q156 Y159 W167 Y171
Binding residue
(residue number reindexed from 1)		Y7 Y9 E63 N66 V67 Q70 D77 Y84 Y99 R114 D116 T143 K146 W147 A150 A152 Q155 Q156 Y159 W167 Y171
Enzymatic activity
Enzyme Commision number ?
External links
PDB RCSB:1q94, PDBe:1q94, PDBj:1q94
PDBsum1q94
PubMed15128805
UniProtP04439|HLAA_HUMAN HLA class I histocompatibility antigen, A alpha chain (Gene Name=HLA-A)

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