Structure of PDB 1q3u Chain A Binding Site BS01

Receptor Information
>1q3u Chain A (length=332) Species: 10678 (Punavirus P1) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
NLPALPVDATSDEVRKNLMDMFRDRQAFSEHTWKMLLSVCRSWAAWCKLN
NRKWFPAEPEDVRDYLLYLQARGLAVKTIQQHLGQLNMLHRRSGLPRPSD
SNAVSLVMRRIRKENVDAGERAKQALAFERTDFDQVRSLMENSDRCQDIR
NLAFLGIAYNTLLRIAEIARIRVKDISRTDGGRMLIHIGRTKTLVSTAGV
EKALSLGVTKLVERWISVSGVADDPNNYLFCRVRKNGVAAPSATSQLSTR
ALEGIFEATHRLIYGAKDDSGQRYLAWSGHSARVGAARDMARAGVSIPEI
MQAGGWTNVNIVMNYIRNLDSETGAMVRLLED
Ligand information
Receptor-Ligand Complex Structure
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PDB1q3u Crystal structure of a wild-type Cre recombinase-loxP synapse reveals a novel spacer conformation suggesting an alternative mechanism for DNA cleavage activation
Resolution2.9 Å
Binding residue
(original residue number in PDB)
F37 S38 H40 T41 M97 R173 I174 A175 K201 R243 K244 N245 R259 E262 K276 R282 S287 G288 H289
Binding residue
(residue number reindexed from 1)
F28 S29 H31 T32 M88 R164 I165 A166 K192 R234 K235 N236 R250 E253 K267 R273 S278 G279 H280
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Biological Process
GO:0006310 DNA recombination
GO:0015074 DNA integration

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Molecular Function

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Biological Process
External links
PDB RCSB:1q3u, PDBe:1q3u, PDBj:1q3u
PDBsum1q3u
PubMed12954782
UniProtP06956|RECR_BPP1 Recombinase cre (Gene Name=cre)

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