Structure of PDB 1q0t Chain A Binding Site BS01

Receptor Information
>1q0t Chain A (length=241) Species: 10665 (Tequatrovirus T4) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MLGAIAYTGNKQSLLPELKSHFPKYNRFVDLFCGGLSVSLNVNGPVLAND
IQEPIIEMYKRLINVSWDDVLKVIKQYKLSKTSKEEFLKLREDYNKTRDP
LLLYVLHFHGFSNMIRINDKGNFTTPFGKRTINKNSEKQYNHFKQNCDKI
IFSSLHFKDVKILDGDFVYVDPPYLITVADYNKFWSEDEEKDLLNLLDSL
NDRGIKFGQSNVLEHHGKENTLLKEWSKKYNVKHLEVYIFN
Ligand information
Receptor-Ligand Complex Structure
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PDB1q0t Structure of the bacteriophage T4 DNA adenine methyltransferase
Resolution3.1 Å
Binding residue
(original residue number in PDB)		R130 N133 K134 N135
Binding residue
(residue number reindexed from 1)		R130 N133 K134 N135
Enzymatic activity
Enzyme Commision number 2.1.1.72: site-specific DNA-methyltransferase (adenine-specific).
Gene Ontology
Molecular Function
GO:0003676 nucleic acid binding
GO:0003677 DNA binding
GO:0008168 methyltransferase activity
GO:0009007 site-specific DNA-methyltransferase (adenine-specific) activity
GO:0009008 DNA-methyltransferase activity
GO:0043565 sequence-specific DNA binding
GO:1904047 S-adenosyl-L-methionine binding
Biological Process
GO:0006260 DNA replication
GO:0006298 mismatch repair
GO:0009307 DNA restriction-modification system
GO:0019049 virus-mediated perturbation of host defense response
GO:0032259 methylation
GO:0052170 symbiont-mediated suppression of host innate immune response
GO:0099018 symbiont-mediated evasion of host restriction-modification system

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Molecular Function
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Biological Process
External links
PDB RCSB:1q0t, PDBe:1q0t, PDBj:1q0t
PDBsum1q0t
PubMed12937411
UniProtP04392|DMA_BPT4 DNA adenine methylase (Gene Name=DAM)

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